An endometrial biopsy is a procedure performed to obtain a small tissue sample from the lining (endometrium) of your uterus to be microscopically examined by a pathologist. An endometrial biopsy may be performed by your provider to assess abnormal uterine bleeding, bleeding after menopause, infertility, or results of a pap smear. The biopsy is performed by using a small straw-like tube through the cervical opening and into the uterine cavity. Using the tube, the provider will take a small sample of cells from the inner layer of the uterine wall.
In preparation for the procedure, DO NOT insert anything into the vaginal canal for 48 hours prior to your procedure including: medications, tampons, sexual intercourse, etc. An endometrial biopsy is preferably not performed when a woman has her period, although light bleeding is permissible.
Anesthesia is not needed for this procedure. It is suggested that you take Ibuprofen 600-800 mg or Aspirin to relieve cramping associated with the procedure, as long as you are not allergic to either. After the procedure, you may resume all normal activity. However, you may experience some spotting for a few days after the procedure; please use a sanitary pad, do not use a tampon. Using a tampon could leave to post operative infection.